Assessing a Model of the Physiological Changes at Arousal From Sleep.

The independent effects of sleep deprivation and sleep fragmentation on processing of emotional information

VV Lee, R Schembri, AS Jordan, ML Jackson

2022-04-29

Disrupted sleep through sleep deprivation or sleep fragmentation has previously been shown to impair cognitive processing. Neverth..

Does nasal obstruction induce obstructive sleep apnea in healthy women?

I Pittaway, A Ishkova, H Bean, S McCarthy, I Lay, J Avraam, A Dawson, T Thornton, CL Nicholas, J Trinder, FJ O’donoghue, ML Jackson, AS Jordan

2020-01-01

Purpose: Obstructive sleep apnea (OSA) is less prevalent among women and is associated with different symptoms and consequences to..

The effect of sex and body weight on lung volumes during sleep

J Avraam, A Dawson, PD Rochford, DJ Brazzale, FJ O'Donoghue, J Trinder, AS Jordan

2019-10-01

Study Objectives: Low lung volumes are thought to contribute to obstructive sleep apnea (OSA). OSA is worse in the supine versus l..

A randomised controlled trial of nasal decongestant to treat obstructive sleep apnoea in people with cervical spinal cord injury

NS Wijesuriya, DJ Eckert, AS Jordan, R Schembri, C Lewis, H Meaklim, L Booker, D Brown, M Graco, DJ Berlowitz

2019-07-01

Study design: Prospective, double-blind, randomised, placebo-controlled, cross-over trial of nasal decongestion in tetraplegia. Ob..

Genioglossus reflex responses to negative upper airway pressure are altered in people with tetraplegia and obstructive sleep apnoea

NS Wijesuriya, L Gainche, AS Jordan, DJ Berlowitz, M LeGuen, PD Rochford, FJ O'Donoghue, WR Ruehland, JC Carberry, JE Butler, DJ Eckert

2018-07-15

Key points: Protective reflexes in the throat area (upper airway) are crucial for breathing. Impairment of these reflexes can caus..

The effects of experimental sleep fragmentation and sleep deprivation on the response of the genioglossus muscle to inspiratory resistive loads

JM Cori, CL Nicholas, J Avraam, V Vien Lee, R Schembri, ML Jackson, AS Jordan

2018-05-01

Study Objectives: Poor upper airway dilator muscle function may contribute to obstructive sleep apnea (OSA). Sleep deprivation red..

Physiology of arousal in obstructive sleep apnea and potential impacts for sedative treatment

AS Jordan, FJ O’Donoghue, JM Cori, J Trinder

2017-10-01

High nasal resistance is stable over time but poorly perceived in people with tetraplegia and obstructive sleep apnoea

NS Wijesuriya, C Lewis, JE Butler, BB Lee, AS Jordan, DJ Berlowitz, DJ Eckert

2017-01-01

Obstructive sleep apnoea (OSA) is highly prevalent in people with tetraplegia. Nasal congestion, a risk factor for OSA, is common ..

The effect of body mass and sex on the accuracy of respiratory magnetometers for measurement of end-expiratory lung volumes

J Avraam, R Bourke, J Trinder, CL Nicholas, D Brazzale, FJ O'Donoghue, PD Rochford, AS Jordan

2016-11-01

Respiratory magnetometers are increasingly being used in sleep studies to measure changes in end-expiratory lung volume (EELV), in..

Nasal Resistance Is Elevated in People with Tetraplegia and Is Reduced by Topical Sympathomimetic Administration

L Gainche, DJ Berlowitz, M Leguen, WR Ruehland, FJ O'Donoghue, J Trinder, M Graco, R Schembri, DJ Eckert, PD Rochford, AS Jordan

2016-01-01

Study Objectives: Obstructive sleep apnea (OSA) is common in individuals with tetraplegia and associated with adverse health outco..

An integrative model of physiological traits can be used to predict obstructive sleep apnea and response to non positive airway pressure therapy

RL Owens, BA Edwards, DJ Eckert, AS Jordan, SA Sands, A Malhotra, DP White, SH Loring, JP Butler, A Wellman

2015-06-01

Study Objectives: Both anatomical and nonanatomical traits are important in obstructive sleep apnea (OSA) pathogenesis. We have pr..

Arousal from sleep does not lead to reduced dilator muscle activity or elevated upper airway resistance on return to sleep in healthy individuals

AS Jordan, JM Cori, A Dawson, CL Nicholas, FJ O'Donoghue, PG Catcheside, DJ Eckert, RD McEvoy, J Trinder

2015-01-01

Study Objectives: To compare changes in end-tidal CO<inf>2</inf>, genioglossus muscle activity and upper airway resistance followi..